3RI5

C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and picrotoxin

3RI5 の概要

• エントリーDOI: 10.2210/pdb3ri5/pdb
• 関連するPDBエントリー: 3RHW
• 分子名称: Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione, Mouse monoclonal Fab fragment, heavy chain, ... (10 entities in total)
• 機能のキーワード: membrane protein, transport protein, cys-loop receptor, ligand-gated ion channel, neurotransmitter receptor, ivermectin, picrotoxin, glycosylation, transport protein-immune system complex, transport protein/immune system
• 由来する生物種: Caenorhabditis elegans (nematode); 詳細
• タンパク質・核酸の鎖数: 15
• 化学式量合計: 438280.31

構造登録者

Hibbs, R.E.,Gouaux, E. (登録日: 2011-04-12, 公開日: 2011-05-25, 最終更新日: 2023-09-13)

• 主引用文献: Hibbs, R.E.,Gouaux, E.; Principles of activation and permeation in an anion-selective Cys-loop receptor.; Nature, 474:54-60, 2011; PubMed: 21572436; DOI: 10.1038/nature10139

実験手法

X-RAY DIFFRACTION (3.4 Å)