3RG2

Structure of a two-domain NRPS fusion protein containing the EntE adenylation domain and EntB aryl-carrier protein from enterobactin biosynthesis

3RG2 の概要

• エントリーDOI: 10.2210/pdb3rg2/pdb
• 分子名称: Enterobactin synthase component E (entE), 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase (Entb), 5'-deoxy-5'-({[2-(2-hydroxyphenyl)ethyl]sulfonyl}amino)adenosine, 4'-PHOSPHOPANTETHEINE, ... (4 entities in total)
• 機能のキーワード: adenylate-forming enzymes, anl superfamily, non-ribosomal peptide synthetase carrier protein function, nrps adenylation domain acyl carrier protein, 4'phosphopantetheinylation 4'pp cofactor, ligase
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 694555.15

構造登録者

Sundlov, J.A.,Gulick, A.M. (登録日: 2011-04-07, 公開日: 2012-03-07, 最終更新日: 2023-09-13)

• 主引用文献: Sundlov, J.A.,Shi, C.,Wilson, D.J.,Aldrich, C.C.,Gulick, A.M.; Structural and Functional Investigation of the Intermolecular Interaction between NRPS Adenylation and Carrier Protein Domains.; Chem.Biol., 19:188-198, 2012; PubMed: 22365602; DOI: 10.1016/j.chembiol.2011.11.013

実験手法

X-RAY DIFFRACTION (3.1 Å)