3RAW

Crystal Structure of human CDC-like kinase 3 isoform in complex with leucettine L41

3RAW の概要

• エントリーDOI: 10.2210/pdb3raw/pdb
• 関連するPDBエントリー: 2EU9
• 分子名称: Dual specificity protein kinase CLK3, 5-(1,3-benzodioxol-5-ylmethyl)-2-(phenylamino)-4H-imidazol-4-one (3 entities in total)
• 機能のキーワード: transferase, kinase, tyrosine-protein kinase, serine/threonine-protein kinase, nucleotide-binding, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: P49761
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 90194.73

構造登録者

Filippakopoulos, P.,Fedorov, O.,King, O.,Debdab, M.,Carreaux, F.,Renault, S.,Bullock, A.,Muniz, J.R.C.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Meijer, L.,Bazureau, J.P.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2011-03-28, 公開日: 2011-05-04, 最終更新日: 2023-09-13)

• 主引用文献: Filippakopoulos, P.,Fedorov, O.,King, O.,Bullock, A.,Muniz, J.R.C.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal Structure of human CDC-like kinase 3 isoform with a benzo-dioxol ligand; To be Published,

実験手法

X-RAY DIFFRACTION (2.09 Å)