3R5Y

Structure of a Deazaflavin-dependent nitroreductase from Nocardia farcinica, with co-factor F420

3R5Y の概要

• エントリーDOI: 10.2210/pdb3r5y/pdb
• 関連するPDBエントリー: 3R5L 3R5P 3R5R 3R5W 3R5Z
• 分子名称: Putative uncharacterized protein, COENZYME F420 (3 entities in total)
• 機能のキーワード: pa-824, nitroimidazoles, split barrel-like fold, duf385, deazaflavin-dependent nitroreductase, f420, unknown function
• 由来する生物種: Nocardia farcinica
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 68423.54

構造登録者

Cellitti, S.E.,Shaffer, J.,Jones, D.H.,Mukherjee, T.,Gurumurthy, M.,Bursulaya, B.,Boshoff, H.I.M.,Choi, I.,Nayya, A.,Lee, Y.S.,Cherian, J.,Niyomrattanakit, P.,Dick, T.,Manjunatha, U.H.,Barry, C.E.,Spraggon, G.,Geierstanger, B.H. (登録日: 2011-03-20, 公開日: 2012-01-18, 最終更新日: 2023-09-13)

• 主引用文献: Cellitti, S.E.,Shaffer, J.,Jones, D.H.,Mukherjee, T.,Gurumurthy, M.,Bursulaya, B.,Boshoff, H.I.,Choi, I.,Nayyar, A.,Lee, Y.S.,Cherian, J.,Niyomrattanakit, P.,Dick, T.,Manjunatha, U.H.,Barry, C.E.,Spraggon, G.,Geierstanger, B.H.; Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824.; Structure, 20:101-112, 2012; PubMed: 22244759; DOI: 10.1016/j.str.2011.11.001

実験手法

X-RAY DIFFRACTION (1.801 Å)