3R5P
Structure of Ddn, the Deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824
Summary for 3R5P
Entry DOI | 10.2210/pdb3r5p/pdb |
Related | 3R5L 3R5R 3R5W 3R5Y 3R5Z |
Descriptor | Deazaflavin-dependent nitroreductase, SULFATE ION (3 entities in total) |
Functional Keywords | pa-824, split barrel-like fold, duf385, deazaflavin-dependent nitroreductase, nitroimidazoles, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 13557.03 |
Authors | Cellitti, S.E.,Shaffer, J.,Jones, D.H.,Mukherjee, T.,Gurumurthy, M.,Bursulaya, B.,Boshoff, H.I.M.,Choi, I.,Nayya, A.,Lee, Y.S.,Cherian, J.,Niyomrattanakit, P.,Dick, T.,Manjunatha, U.H.,Barry, C.E.,Spraggon, G.,Geierstanger, B.H. (deposition date: 2011-03-19, release date: 2012-01-18, Last modification date: 2023-12-06) |
Primary citation | Cellitti, S.E.,Shaffer, J.,Jones, D.H.,Mukherjee, T.,Gurumurthy, M.,Bursulaya, B.,Boshoff, H.I.,Choi, I.,Nayyar, A.,Lee, Y.S.,Cherian, J.,Niyomrattanakit, P.,Dick, T.,Manjunatha, U.H.,Barry, C.E.,Spraggon, G.,Geierstanger, B.H. Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824. Structure, 20:101-112, 2012 Cited by PubMed: 22244759DOI: 10.1016/j.str.2011.11.001 PDB entries with the same primary citation |
Experimental method |
Structure validation
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