3R4T

Crystal structure of 4-aminobutyrate aminotransferase GabT from Mycobacterium marinum covalently bound to pyridoxal phosphate

3R4T の概要

• エントリーDOI: 10.2210/pdb3r4t/pdb
• 関連するPDBエントリー: 3OKS 3Q8N
• 分子名称: 4-aminobutyrate aminotransferase GabT, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: structural genomics, seattle structural genomics center for infectious disease, ssgcid, mycobacterium, tuberculosis, smegmatis, marinum, water contaminant, pyridoxal phosphate, plp, llp, gamma amino butyric acid, gaba, gaba transferase, gabaculine, phenelzine, aminooxyacetic acid, phenylethylidenehydrazine, vigabatrin, valproic acid, transferase
• 由来する生物種: Mycobacterium marinum
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 50042.39

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2011-03-17, 公開日: 2011-03-30, 最終更新日: 2023-12-06)

• 主引用文献: Baugh, L.,Phan, I.,Begley, D.W.,Clifton, M.C.,Armour, B.,Dranow, D.M.,Taylor, B.M.,Muruthi, M.M.,Abendroth, J.,Fairman, J.W.,Fox, D.,Dieterich, S.H.,Staker, B.L.,Gardberg, A.S.,Choi, R.,Hewitt, S.N.,Napuli, A.J.,Myers, J.,Barrett, L.K.,Zhang, Y.,Ferrell, M.,Mundt, E.,Thompkins, K.,Tran, N.,Lyons-Abbott, S.,Abramov, A.,Sekar, A.,Serbzhinskiy, D.,Lorimer, D.,Buchko, G.W.,Stacy, R.,Stewart, L.J.,Edwards, T.E.,Van Voorhis, W.C.,Myler, P.J.; Increasing the structural coverage of tuberculosis drug targets.; Tuberculosis (Edinb), 95:142-148, 2015; PubMed: 25613812; DOI: 10.1016/j.tube.2014.12.003

実験手法

X-RAY DIFFRACTION (2.5 Å)