3R08

Crystal structure of mouse cd3epsilon in complex with antibody 2C11 Fab

Summary for 3R08

Entry DOI	10.2210/pdb3r08/pdb
Related	3R06
Descriptor	Mouse anti-mouse CD3epsilon antibody 2C11 light chain, Mouse anti-mouse CD3epsilon antibody 2C11 heavy chain, T-cell surface glycoprotein CD3 epsilon chain (3 entities in total)
Functional Keywords	cd3epsilon, antibody, t-cell receptor, signalling, immune system
Biological source	Cricetulus migratorius More
Cellular location	Membrane; Single-pass type I membrane protein: P22646
Total number of polymer chains	3
Total formula weight	56258.54
Authors	Shore, D.A.,Zhu, X.,Wilson, I.A. (deposition date: 2011-03-07, release date: 2012-01-25, Last modification date: 2023-09-13)
Primary citation	Fernandes, R.A.,Shore, D.A.,Vuong, M.T.,Yu, C.,Zhu, X.,Pereira-Lopes, S.,Brouwer, H.,Fennelly, J.A.,Jessup, C.M.,Evans, E.J.,Wilson, I.A.,Davis, S.J. T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements. J.Biol.Chem., 287:13324-13335, 2012 Cited by PubMed: 22262845 DOI: 10.1074/jbc.M111.332783 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.1 Å)

Structure validation