3R08

Crystal structure of mouse cd3epsilon in complex with antibody 2C11 Fab

3R08 の概要

• エントリーDOI: 10.2210/pdb3r08/pdb
• 関連するPDBエントリー: 3R06
• 分子名称: Mouse anti-mouse CD3epsilon antibody 2C11 light chain, Mouse anti-mouse CD3epsilon antibody 2C11 heavy chain, T-cell surface glycoprotein CD3 epsilon chain (3 entities in total)
• 機能のキーワード: cd3epsilon, antibody, t-cell receptor, signalling, immune system
• 由来する生物種: Cricetulus migratorius; 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P22646
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 56258.54

構造登録者

Shore, D.A.,Zhu, X.,Wilson, I.A. (登録日: 2011-03-07, 公開日: 2012-01-25, 最終更新日: 2023-09-13)

• 主引用文献: Fernandes, R.A.,Shore, D.A.,Vuong, M.T.,Yu, C.,Zhu, X.,Pereira-Lopes, S.,Brouwer, H.,Fennelly, J.A.,Jessup, C.M.,Evans, E.J.,Wilson, I.A.,Davis, S.J.; T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements.; J.Biol.Chem., 287:13324-13335, 2012; PubMed: 22262845; DOI: 10.1074/jbc.M111.332783

実験手法

X-RAY DIFFRACTION (4.1 Å)