3QWI

Crystal structure of a 17beta-hydroxysteroid dehydrogenase (holo form) from fungus Cochliobolus lunatus in complex with NADPH and coumestrol

3QWI の概要

• エントリーDOI: 10.2210/pdb3qwi/pdb
• 関連するPDBエントリー: 3IS3 3ITD 3QWF 3QWH
• 分子名称: 17beta-hydroxysteroid dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Coumestrol, ... (5 entities in total)
• 機能のキーワード: 17beta-hydroxysteroid dehydrogenase, short chain dehydrogenase/reductase, phytoestrogens, flavonoid, rossmann fold, cytosol, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Cochliobolus lunatus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 120083.07

構造登録者

Cassetta, A.,Lamba, D.,Krastanova, I.,Stojan, J.,Lanisnik Rizner, T.,Kristan, K.,Brunskole, M. (登録日: 2011-02-28, 公開日: 2012-01-18, 最終更新日: 2023-09-13)

• 主引用文献: Cassetta, A.,Krastanova, I.,Kristan, K.,Brunskole Svegelj, M.,Lamba, D.,Lanisnik Rizner, T.,Stojan, J.; Structural studies on the flavonoid inhibition of a fungal 17Beta-Hydroxysteroid dehydrogenase; Biochem.J., 441:151-160, 2012; PubMed: 21929506; DOI: 10.1042/BJ20110567

実験手法

X-RAY DIFFRACTION (2.5 Å)