3QUO

Crystal structure of fosfomycin resistance kinase FomA from Streptomyces wedmorensis complexed with ATP and fosfomycin

3QUO の概要

• エントリーDOI: 10.2210/pdb3quo/pdb
• 関連するPDBエントリー: 3D40 3D41 3QUN 3QUR 3QVF 3QVH
• 分子名称: FomA protein, ADENOSINE-5'-TRIPHOSPHATE, FOSFOMYCIN, ... (4 entities in total)
• 機能のキーワード: fosfomycin, antibiotic resistance, phosphoryl transfer, kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Streptomyces wedmorensis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 31522.09

構造登録者

Pakhomova, S.,Bartlett, S.G.,Doerner, P.A.,Newcomer, M.E. (登録日: 2011-02-24, 公開日: 2011-07-20, 最終更新日: 2023-09-13)

• 主引用文献: Pakhomova, S.,Bartlett, S.G.,Doerner, P.A.,Newcomer, M.E.; Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.; Biochemistry, 50:6909-6919, 2011; PubMed: 21728358; DOI: 10.1021/bi2004334

実験手法

X-RAY DIFFRACTION (1.58 Å)