3QTE
Crystal structure of human alpha-defensin 6 (H27W mutant)
Summary for 3QTE
Entry DOI | 10.2210/pdb3qte/pdb |
Related | 1ZMP 1ZMQ |
Descriptor | Defensin-6, CHLORIDE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | antimicrobial protein, paneth cells defensin, hd6, human alpha defensin |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: Q01524 |
Total number of polymer chains | 4 |
Total formula weight | 15232.47 |
Authors | Pazgier, M.,Lu, W. (deposition date: 2011-02-22, release date: 2012-01-11, Last modification date: 2023-09-13) |
Primary citation | Chu, H.,Pazgier, M.,Jung, G.,Nuccio, S.P.,Castillo, P.A.,de Jong, M.F.,Winter, M.G.,Winter, S.E.,Wehkamp, J.,Shen, B.,Salzman, N.H.,Underwood, M.A.,Tsolis, R.M.,Young, G.M.,Lu, W.,Lehrer, R.I.,Baumler, A.J.,Bevins, C.L. Human alpha-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets. Science, 337:477-481, 2012 Cited by PubMed: 22722251DOI: 10.1126/science.1218831 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.949 Å) |
Structure validation
Download full validation report