3QSL

Structure of CAE31940 from Bordetella bronchiseptica RB50

Summary for 3QSL

• Entry DOI: 10.2210/pdb3qsl/pdb
• Descriptor: Putative exported protein, CITRIC ACID (3 entities in total)
• Functional Keywords: unknown, structural genomics, psi-biology, midwest center for structural genomics, mcsg, unknown function
• Biological source: Bordetella bronchiseptica
• Total number of polymer chains: 2
• Total formula weight: 72887.07

Authors

Bajor, J.,Kagan, O.,Chruszcz, M.,Savchenko, A.,Joachimiak, A.,Minor, W.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2011-02-21, release date: 2011-03-23, Last modification date: 2023-12-06)

Primary citation

Bajor, J.,Tkaczuk, K.L.,Chruszcz, M.,Chapman, H.,Kagan, O.,Savchenko, A.,Minor, W.
The crystal structure of pyrimidine/thiamin biosynthesis precursor-like domain-containing protein CAE31940 from proteobacterium Bordetella bronchiseptica RB50, and evolutionary insight into the NMT1/THI5 family.
J Struct Funct Genomics, 15:73-81, 2014

PubMed Abstract: We report a 2.0 Å structure of the CAE31940 protein, a proteobacterial NMT1/THI5-like domain-containing protein. We also discuss the primary and tertiary structure similarity with its homologs. The highly conserved FGGXMP motif was identified in CAE31940, which corresponds to the GCCCX motif located in the vicinity of the active center characteristic for THi5-like proteins found in yeast. This suggests that the FGGXMP motif may be a unique hallmark of proteobacterial NMT1/THI5-like proteins.

PubMed: 24908050
DOI: 10.1007/s10969-014-9180-3

Experimental method

X-RAY DIFFRACTION (2 Å)