3QS8
Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS174)
3QS8 の概要
エントリーDOI | 10.2210/pdb3qs8/pdb |
関連するPDBエントリー | 1zvw 2bpq 3QQS 3QR9 3QSA |
分子名称 | Anthranilate phosphoribosyltransferase, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, ... (5 entities in total) |
機能のキーワード | anthranilate phosphoribosyltransferase, anthranilic acids, magnesium, tryptophan, magnesium binding phosphoribosyl pyrophosphate, transferase-transferase inhibitor complex, structural genomics, tb structural genomics consortium, tbsgc, transferase/transferase inhibitor |
由来する生物種 | Mycobacterium tuberculosis |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 157898.94 |
構造登録者 | Castell, A.,Short, F.L.,Lott, J.S.,TB Structural Genomics Consortium (TBSGC) (登録日: 2011-02-20, 公開日: 2012-08-22, 最終更新日: 2024-02-21) |
主引用文献 | Castell, A.,Short, F.L.,Evans, G.L.,Cookson, T.V.,Bulloch, E.M.,Joseph, D.D.,Lee, C.E.,Parker, E.J.,Baker, E.N.,Lott, J.S. The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition. Biochemistry, 52:1776-1787, 2013 Cited by PubMed: 23363292DOI: 10.1021/bi301387m 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2 Å) |
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