3QP8

Crystal structure of CviR (Chromobacterium violaceum 12472) ligand-binding domain bound to C10-HSL

Summary for 3QP8

Entry DOI	10.2210/pdb3qp8/pdb
Related	3QP1 3QP2 3QP4 3QP5 3QP6 3QP7
Descriptor	CviR transcriptional regulator, N-[(3S)-2-oxotetrahydrofuran-3-yl]decanamide (3 entities in total)
Functional Keywords	quorum sensing, agonist, antagonist, luxr, acylated homoserine lactone, transcription factor, dna binding protein, ligand binding domain, signal receptor, quorum sensing transcription receptor, n-decanoyl-l-homoserine lactone, transcription
Biological source	Chromobacterium violaceum
Total number of polymer chains	4
Total formula weight	82281.19
Authors	Chen, G.,Swem, L.,Swem, D.,Stauff, D.,O'Loughlin, C.,Jeffrey, P.,Bassler, B.,Hughson, F. (deposition date: 2011-02-11, release date: 2011-03-30, Last modification date: 2023-09-13)
Primary citation	Chen, G.,Swem, L.R.,Swem, D.L.,Stauff, D.L.,O'Loughlin, C.T.,Jeffrey, P.D.,Bassler, B.L.,Hughson, F.M. A strategy for antagonizing quorum sensing. Mol.Cell, 42:199-209, 2011 Cited by PubMed: 21504831 DOI: 10.1016/j.molcel.2011.04.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation