3QMH

Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-TCGA) by the CXXC Domain of CFP1

Summary for 3QMH

• Entry DOI: 10.2210/pdb3qmh/pdb
• Related: 3QMB 3QMC 3QMD 3QMG 3QMI
• Descriptor: CpG-binding protein, 5'-D(*GP*CP*CP*AP*TP*CP*GP*AP*TP*GP*GP*C)-3', ZINC ION, ... (4 entities in total)
• Functional Keywords: structural genomics consortium, sgc, dna binding, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus speckle: Q9P0U4
• Total number of polymer chains: 3
• Total formula weight: 16985.56

Authors

Xu, C.,Bian, C.,MacKenzie, F.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2011-02-04, release date: 2011-02-23, Last modification date: 2023-09-13)

• Primary citation: Xu, C.,Bian, C.,Lam, R.,Dong, A.,Min, J.; The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.; Nat Commun, 2:227-227, 2011; PubMed: 21407193; DOI: 10.1038/ncomms1237

Experimental method

X-RAY DIFFRACTION (2.5 Å)