3QI8
Evolved variant of cytochrome P450 (BM3, CYP102A1)
Summary for 3QI8
| Entry DOI | 10.2210/pdb3qi8/pdb |
| Descriptor | Evolved Cytochrome P450 variant (22A3), PROTOPORPHYRIN IX CONTAINING FE (2 entities in total) |
| Functional Keywords | cytochrome p450, oxidation (naproxen, ibuprofen), oxidoreductase |
| Biological source | Bacillus megaterium |
| Total number of polymer chains | 2 |
| Total formula weight | 109548.52 |
| Authors | Rentmeister, A.,Brown, T.R.,Snow, C.D.,Carbone, M.N.,Arnold, F.H. (deposition date: 2011-01-26, release date: 2011-05-04, Last modification date: 2023-09-13) |
| Primary citation | Rentmeister, A.,Brown, T.R.,Snow, C.D.,Carbone, M.N.,Arnold, F.H. Engineered Bacterial Mimics of Human Drug Metabolizing Enzyme CYP2C9 Chemcatchem, 2011 Cited by DOI: 10.1002/cctc.201000452PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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