3QGL

Crystal Structure of PDZ domain of sorting nexin 27 (SNX27) in complex with the ESESKV peptide corresponding to the C-terminal tail of GIRK3

3QGL の概要

• エントリーDOI: 10.2210/pdb3qgl/pdb
• 関連するPDBエントリー: 3QDO 3QE1
• 分子名称: Sorting nexin-27, G protein-activated inward rectifier potassium channel 3 (3 entities in total)
• 機能のキーワード: pdz domain, pdz binding, girk3 regulation, early endosomes, brain, neurons, protein binding
• 由来する生物種: Rattus norvegicus (rat); 詳細
• 細胞内の位置: Cytoplasm, cytosol: Q8K4V4; Membrane; Multi-pass membrane protein: Q63511
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 56243.30

構造登録者

Balana, B.,Kwiatkowski, W.,Choe, S. (登録日: 2011-01-24, 公開日: 2011-03-16, 最終更新日: 2023-09-13)

• 主引用文献: Balana, B.,Maslennikov, I.,Kwiatkowski, W.,Stern, K.M.,Bahima, L.,Choe, S.,Slesinger, P.A.; Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27.; Proc.Natl.Acad.Sci.USA, 108:5831-5836, 2011; PubMed: 21422294; DOI: 10.1073/pnas.1018645108

実験手法

X-RAY DIFFRACTION (3.31 Å)