3QEM

Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in complex with Ro 25-6981

3QEM の概要

• エントリーDOI: 10.2210/pdb3qem/pdb
• 関連するPDBエントリー: 3JPW 3QEK 3QEL
• 分子名称: NMDA glutamate receptor subunit, Glutamate [NMDA] receptor subunit epsilon-2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: ion channel, nmda receptor, allosteric modulation, phenylethanolamine, n-glycosylation, extracellular, transmembrane, transport protein
• 由来する生物種: Xenopus laevis (African clawed frog); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 171341.70

構造登録者

Karakas, E.,Simorowski, N.,Furukawa, H. (登録日: 2011-01-20, 公開日: 2011-06-15, 最終更新日: 2023-09-13)

• 主引用文献: Karakas, E.,Simorowski, N.,Furukawa, H.; Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.; Nature, 475:249-253, 2011; PubMed: 21677647; DOI: 10.1038/nature10180

実験手法

X-RAY DIFFRACTION (3.003 Å)