3Q99
Structure of neuronal nitric oxide synthase in the ferric state in complex with N~5~-[(3-(ethylsulfanyl)propanimidoyl]-L-ornithine
Summary for 3Q99
Entry DOI | 10.2210/pdb3q99/pdb |
Related | 3JT4 3Q9A |
Descriptor | Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, N~5~-[(3-(ethylsulfanyl)propanimidoyl]-L-ornithine, ... (7 entities in total) |
Functional Keywords | nitric oxide synthase, heme enzyme, oxidoreductase, inhibitor, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Rattus norvegicus (Rat) |
Cellular location | Cell membrane, sarcolemma ; Peripheral membrane protein : P29476 |
Total number of polymer chains | 2 |
Total formula weight | 100018.74 |
Authors | Li, H.,Doukov, T.,Poulos, T.L. (deposition date: 2011-01-07, release date: 2011-05-18, Last modification date: 2023-09-13) |
Primary citation | Doukov, T.,Li, H.,Sharma, A.,Martell, J.D.,Soltis, S.M.,Silverman, R.B.,Poulos, T.L. Temperature-dependent spin crossover in neuronal nitric oxide synthase bound with the heme-coordinating thioether inhibitors. J.Am.Chem.Soc., 133:8326-8334, 2011 Cited by PubMed: 21534614DOI: 10.1021/ja201466v PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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