3Q76

Structure of human neutrophil elastase (uncomplexed)

Summary for 3Q76

• Entry DOI: 10.2210/pdb3q76/pdb
• Related: 3Q77
• Descriptor: Neutrophil elastase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: trypsin family fold, protease, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 49278.16

Authors

Hansen, G.,Niefind, K. (deposition date: 2011-01-04, release date: 2011-05-11, Last modification date: 2023-09-13)

• Primary citation: Hansen, G.,Gielen-Haertwig, H.,Reinemer, P.,Schomburg, D.,Harrenga, A.,Niefind, K.; Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor.; J.Mol.Biol., 409:681-691, 2011; PubMed: 21549129; DOI: 10.1016/j.jmb.2011.04.047

Experimental method

X-RAY DIFFRACTION (1.861 Å)