3Q71

Human parp14 (artd8) - macro domain 2 in complex with adenosine-5-diphosphoribose

3Q71 の概要

• エントリーDOI: 10.2210/pdb3q71/pdb
• 分子名称: Poly [ADP-ribose] polymerase 14, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE (3 entities in total)
• 機能のキーワード: structural genomics, structural genomics consortium, sgc, transferase, parp14 macro 2
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus : Q460N5
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24896.01

構造登録者

Karlberg, T.,Siponen, M.I.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Ekblad, T.,Flodin, S.,Flores, A.,Graslund, S.,Kotenyova, T.,Kouznetsova, E.,Moche, M.,Nordlund, P.,Nyman, T.,Persson, C.,Sehic, A.,Thorsell, A.G.,Tresaugues, L.,Wahlberg, E.,Weigelt, J.,Welin, M.,Schuler, H.,Structural Genomics Consortium (SGC) (登録日: 2011-01-04, 公開日: 2011-01-26, 最終更新日: 2023-09-13)

• 主引用文献: Forst, A.H.,Karlberg, T.,Herzog, N.,Thorsell, A.G.,Gross, A.,Feijs, K.L.,Verheugd, P.,Kursula, P.,Nijmeijer, B.,Kremmer, E.,Kleine, H.,Ladurner, A.G.,Schuler, H.,Luscher, B.; Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains.; Structure, 21:462-475, 2013; PubMed: 23473667; DOI: 10.1016/j.str.2012.12.019

実験手法

X-RAY DIFFRACTION (2.2 Å)