3Q6E

Human insulin in complex with cucurbit[7]uril

3Q6E の概要

• エントリーDOI: 10.2210/pdb3q6e/pdb
• 分子名称: Insulin A chain, Insulin B chain, cucurbit[7]uril, ... (4 entities in total)
• 機能のキーワード: insulin, cucurbit[7]uril, cucurbituril, synthetic, host, phenylalanine, supramolecular, recognition, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, disulfide bond, glucose metabolism, hormone, secreted
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P01308 P01308
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 12798.26

構造登録者

Chinai, J.M.,Taylor, A.B.,Hargreaves, N.D.,Ryno, L.M.,Morris, C.A.,Hart, P.J.,Urbach, A.R. (登録日: 2010-12-31, 公開日: 2011-04-20, 最終更新日: 2023-09-13)

• 主引用文献: Chinai, J.M.,Taylor, A.B.,Ryno, L.M.,Hargreaves, N.D.,Morris, C.A.,Hart, P.J.,Urbach, A.R.; Molecular recognition of insulin by a synthetic receptor.; J.Am.Chem.Soc., 133:8810-8813, 2011; PubMed: 21473587; DOI: 10.1021/ja201581x

実験手法

X-RAY DIFFRACTION (2.05 Å)