3Q2K

Crystal structure of the WlbA dehydrogenase from Bordetella pertussis in complex with NADH and UDP-GlcNAcA

3Q2K の概要

• エントリーDOI: 10.2210/pdb3q2k/pdb
• 関連するPDBエントリー: 3Q2I
• 分子名称: oxidoreductase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, (2S,3S,4R,5R,6R)-5-acetamido-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4-dihydroxy-oxane-2-carboxylic acid, ... (4 entities in total)
• 機能のキーワード: rossmann fold, dehydrogenase, nad, udp-sugar, oxidoreductase
• 由来する生物種: Bordetella pertussis
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 680579.07

構造登録者

Holden, H.M.,Thoden, J.B. (登録日: 2010-12-20, 公開日: 2011-01-19, 最終更新日: 2023-09-13)

• 主引用文献: Thoden, J.B.,Holden, H.M.; Biochemical and Structural Characterization of WlbA from Bordetella pertussis and Chromobacterium violaceum: Enzymes Required for the Biosynthesis of 2,3-Diacetamido-2,3-dideoxy-d-mannuronic Acid.; Biochemistry, 50:1483-1491, 2011; PubMed: 21241053; DOI: 10.1021/bi101871f

実験手法

X-RAY DIFFRACTION (2.13 Å)