3Q2E
Crystal structure of the second bromodomain of human bromodomain and WD repeat-containing protein 1 isoform A (WDR9)
Summary for 3Q2E
Entry DOI | 10.2210/pdb3q2e/pdb |
Descriptor | Bromodomain and WD repeat-containing protein 1, ACETATE ION (3 entities in total) |
Functional Keywords | structural genomics consortium, sgc, bromodomain, cell cycle progression, signal transduction, apoptosis, gene regulation, down syndrome region-2 on chromosome 21, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9NSI6 |
Total number of polymer chains | 1 |
Total formula weight | 14506.45 |
Authors | Filippakopoulos, P.,Felletar, I.,Picaud, S.,Keates, T.,Krojer, T.,Muniz, J.,Gileadi, O.,Von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2010-12-20, release date: 2011-02-16, Last modification date: 2023-11-01) |
Primary citation | Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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