3Q2C

Binding properties to HLA class I molecules and the structure of the leukocyte Ig-like receptor A3 (LILRA3/ILT6/LIR4/CD85e)

Summary for 3Q2C

• Entry DOI: 10.2210/pdb3q2c/pdb
• Related: 1VDG
• Descriptor: Leukocyte immunoglobulin-like receptor subfamily A member 3 (2 entities in total)
• Functional Keywords: lilra3, ilt6, activating receptor, hla binding, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 10792.34

Authors

Ryu, M.,Chen, Y.,Qi, J.X.,Liu, J.,Shi, Y.,Cheng, H.,Gao, G.F. (deposition date: 2010-12-20, release date: 2011-07-13, Last modification date: 2023-11-01)

• Primary citation: Ryu, M.,Chen, Y.,Qi, J.,Liu, J.,Fan, Z.,Nam, G.,Shi, Y.,Cheng, H.,Gao, G.F.; LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1/LILRB2: structural evidence; Plos One, 6:e19245-e19245, 2011; PubMed: 21559424; DOI: 10.1371/journal.pone.0019245

Experimental method

X-RAY DIFFRACTION (2.5 Å)