3PQZ
Grb7 SH2 with peptide
Summary for 3PQZ
Entry DOI | 10.2210/pdb3pqz/pdb |
Descriptor | Growth factor receptor-bound protein 7, cyclic peptide (3 entities in total) |
Functional Keywords | sh2, binds phosphotyrosine, tyrosine kinases, cytoplasmic, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 56670.86 |
Authors | Wilce, J.A. (deposition date: 2010-11-29, release date: 2011-07-20, Last modification date: 2011-09-21) |
Primary citation | Ambaye, N.D.,Pero, S.C.,Gunzburg, M.J.,Yap, M.,Clayton, D.J.,Del Borgo, M.P.,Perlmutter, P.,Aguilar, M.I.,Shukla, G.S.,Peletskaya, E.,Cookson, M.M.,Krag, D.N.,Wilce, M.C.,Wilce, J.A. Structural basis of binding by cyclic nonphosphorylated Peptide antagonists of grb7 implicated in breast cancer progression J.Mol.Biol., 412:397-411, 2011 Cited by PubMed: 21802427DOI: 10.1016/j.jmb.2011.07.030 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.413 Å) |
Structure validation
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