3PQZ

Grb7 SH2 with peptide

3PQZ の概要

• エントリーDOI: 10.2210/pdb3pqz/pdb
• 分子名称: Growth factor receptor-bound protein 7, cyclic peptide (3 entities in total)
• 機能のキーワード: sh2, binds phosphotyrosine, tyrosine kinases, cytoplasmic, protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 56670.86

構造登録者

Wilce, J.A. (登録日: 2010-11-29, 公開日: 2011-07-20, 最終更新日: 2011-09-21)

• 主引用文献: Ambaye, N.D.,Pero, S.C.,Gunzburg, M.J.,Yap, M.,Clayton, D.J.,Del Borgo, M.P.,Perlmutter, P.,Aguilar, M.I.,Shukla, G.S.,Peletskaya, E.,Cookson, M.M.,Krag, D.N.,Wilce, M.C.,Wilce, J.A.; Structural basis of binding by cyclic nonphosphorylated Peptide antagonists of grb7 implicated in breast cancer progression; J.Mol.Biol., 412:397-411, 2011; PubMed: 21802427; DOI: 10.1016/j.jmb.2011.07.030

実験手法

X-RAY DIFFRACTION (2.413 Å)