3PNA

Crystal Structure of cAMP bound (91-244)RIa Subunit of cAMP-dependent Protein Kinase

3PNA の概要

• エントリーDOI: 10.2210/pdb3pna/pdb
• 関連するPDBエントリー: 1NE4 1RGS
• 分子名称: cAMP-dependent protein kinase type I-alpha regulatory subunit, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: beta-barrel, camp-binding, catalytic subunit, transferase
• 由来する生物種: Bos taurus (bovine,cow,domestic cattle,domestic cow)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 35429.63

構造登録者

Kim, C.,Taylor, S. (登録日: 2010-11-18, 公開日: 2011-02-09, 最終更新日: 2024-02-21)

• 主引用文献: Badireddy, S.,Yunfeng, G.,Ritchie, M.,Akamine, P.,Wu, J.,Kim, C.W.,Taylor, S.S.,Qingsong, L.,Swaminathan, K.,Anand, G.S.; Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design.; Mol Cell Proteomics, 10:M110.004390-M110.004390, 2011; PubMed: 21081668; DOI: 10.1074/mcp.M110.004390

実験手法

X-RAY DIFFRACTION (1.503 Å)