3PKX

Crystal Structure of Toxoflavin Lyase (TflA) bound to Mn(II) and Toxoflavin

Summary for 3PKX

• Entry DOI: 10.2210/pdb3pkx/pdb
• Related: 3PKV 3PKW
• Descriptor: Toxoflavin lyase (TflA), MANGANESE (II) ION, 1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione, ... (4 entities in total)
• Functional Keywords: metalloenzyme, vicinal oxygen chelate superfamily, lyase
• Biological source: Paenibacillus Polymyxa
• Total number of polymer chains: 1
• Total formula weight: 28575.86

Authors

Fenwick, M.K.,Philmus, B.,Begley, T.P.,Ealick, S.E. (deposition date: 2010-11-12, release date: 2011-01-12, Last modification date: 2024-02-21)

• Primary citation: Fenwick, M.K.,Philmus, B.,Begley, T.P.,Ealick, S.E.; Toxoflavin lyase requires a novel 1-his-2-carboxylate facial triad .; Biochemistry, 50:1091-1100, 2011; PubMed: 21166463; DOI: 10.1021/bi101741v

Experimental method

X-RAY DIFFRACTION (1.5 Å)