3PJG
Crystal structure of UDP-glucose dehydrogenase from Klebsiella pneumoniae complexed with product UDP-glucuronic acid
Summary for 3PJG
Entry DOI | 10.2210/pdb3pjg/pdb |
Related | 1DLI 3PHL 3PID |
Descriptor | UDP-glucose 6-dehydrogenase, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID, ... (4 entities in total) |
Functional Keywords | rossmann fold, dehydrogenase, oxidoreductase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 48767.55 |
Authors | Chen, Y.-Y.,Ko, T.-P.,Lin, C.-H.,Chen, W.-H.,Wang, A.H.-J. (deposition date: 2010-11-10, release date: 2011-09-28, Last modification date: 2023-11-01) |
Primary citation | Chen, Y.Y.,Ko, T.P.,Lin, C.H.,Chen, W.H.,Wang, A.H. Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance. J.Struct.Biol., 175:300-310, 2011 Cited by PubMed: 21536136DOI: 10.1016/j.jsb.2011.04.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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