3PGT

CRYSTAL STRUCTURE OF HGSTP1-1[I104] COMPLEXED WITH THE GSH CONJUGATE OF (+)-ANTI-BPDE

3PGT の概要

• エントリーDOI: 10.2210/pdb3pgt/pdb
• 関連するPDBエントリー: 1PGT 2PGT 4PGT
• 分子名称: PROTEIN (GLUTATHIONE S-TRANSFERASE), SULFATE ION, 2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7,8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID, ... (5 entities in total)
• 機能のキーワード: transferase, pi class, hgstp1-1[i104], detoxification
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 49420.16

構造登録者

Ji, X.,Xiao, B. (登録日: 1999-03-22, 公開日: 1999-09-01, 最終更新日: 2023-09-06)

• 主引用文献: Ji, X.,Blaszczyk, J.,Xiao, B.,O'Donnell, R.,Hu, X.,Herzog, C.,Singh, S.V.,Zimniak, P.; Structure and function of residue 104 and water molecules in the xenobiotic substrate-binding site in human glutathione S-transferase P1-1.; Biochemistry, 38:10231-10238, 1999; PubMed: 10441116; DOI: 10.1021/bi990668u

実験手法

X-RAY DIFFRACTION (2.14 Å)