3PF3
Crystal structure of a mutant (C202A) of Triosephosphate isomerase from Giardia lamblia derivatized with MMTS
Summary for 3PF3
Entry DOI | 10.2210/pdb3pf3/pdb |
Related | 2DP3 |
Descriptor | Triosephosphate isomerase, SULFATE ION, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | triosephosphate isomerase, giardia, isomerase, alpha/beta barrel, thiomethylation, alfa/beta barrel, thiomethylation of cys14, cys222, cys 228 |
Biological source | Giardia intestinalis (Giardia intestinalis) |
Total number of polymer chains | 1 |
Total formula weight | 28739.07 |
Authors | Enriquez-Flores, S.,Rodriguez-Romero, A.,Hernandez-Santoyo, A.,Reyes-Vivas, H. (deposition date: 2010-10-27, release date: 2011-06-22, Last modification date: 2023-09-06) |
Primary citation | Enriquez-Flores, S.,Rodriguez-Romero, A.,Hernandez-Alcantara, G.,Oria-Hernandez, J.,Gutierrez-Castrellon, P.,Perez-Hernandez, G.,Mora-Ide, L.,Castillo-Villanueva, A.,Garcia-Torres, I.,Mendez, S.T.,Gomez-Manzo, S.,Torres-Arroyo, A.,Lopez-Velazquez, G.,Reyes-Vivas, H. Determining the molecular mechanism of inactivation by chemical modification of triosephosphate isomerase from the human parasite Giardia lamblia: A study for antiparasitic drug design. Proteins, 79:2711-2724, 2011 Cited by PubMed: 21786322DOI: 10.1002/prot.23100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.098 Å) |
Structure validation
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