3PF3

Crystal structure of a mutant (C202A) of Triosephosphate isomerase from Giardia lamblia derivatized with MMTS

3PF3 の概要

• エントリーDOI: 10.2210/pdb3pf3/pdb
• 関連するPDBエントリー: 2DP3
• 分子名称: Triosephosphate isomerase, SULFATE ION, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: triosephosphate isomerase, giardia, isomerase, alpha/beta barrel, thiomethylation, alfa/beta barrel, thiomethylation of cys14, cys222, cys 228
• 由来する生物種: Giardia intestinalis (Giardia intestinalis)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28739.07

構造登録者

Enriquez-Flores, S.,Rodriguez-Romero, A.,Hernandez-Santoyo, A.,Reyes-Vivas, H. (登録日: 2010-10-27, 公開日: 2011-06-22, 最終更新日: 2023-09-06)

• 主引用文献: Enriquez-Flores, S.,Rodriguez-Romero, A.,Hernandez-Alcantara, G.,Oria-Hernandez, J.,Gutierrez-Castrellon, P.,Perez-Hernandez, G.,Mora-Ide, L.,Castillo-Villanueva, A.,Garcia-Torres, I.,Mendez, S.T.,Gomez-Manzo, S.,Torres-Arroyo, A.,Lopez-Velazquez, G.,Reyes-Vivas, H.; Determining the molecular mechanism of inactivation by chemical modification of triosephosphate isomerase from the human parasite Giardia lamblia: A study for antiparasitic drug design.; Proteins, 79:2711-2724, 2011; PubMed: 21786322; DOI: 10.1002/prot.23100

実験手法

X-RAY DIFFRACTION (2.098 Å)