3PBW

Crystal structure of the mutant L123N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate

3PBW の概要

• エントリーDOI: 10.2210/pdb3pbw/pdb
• 関連するPDBエントリー: 3G18 3LHW 3LTP 3LTS 3LTY 3LV5 3LV6 3NQ6 3NQ7 3NQA 3NQC 3NQD 3NQE 3NQF 3NQG 3NQM 3P5Y 3P5Z 3P60 3P61 3PBU 3PBV 3PBY 3PC0 3SIZ 3SY5
• 分子名称: Orotidine 5'-monophosphate decarboxylase, 6-AZA URIDINE 5'-MONOPHOSPHATE (3 entities in total)
• 機能のキーワード: tim barrel, orotidine 5'-monophosphate decarboxylase, 6-azauridine 5'-monophosphate, lyase
• 由来する生物種: Methanobacterium thermoautotrophicum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 50421.62

構造登録者

Fedorov, A.A.,Fedorov, E.V.,Iiams, V.,Wood, B.M.,Gerlt, J.A.,Almo, S.C. (登録日: 2010-10-21, 公開日: 2011-09-21, 最終更新日: 2023-09-06)

• 主引用文献: Iiams, V.,Desai, B.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A.; Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site.; Biochemistry, 50:8497-8507, 2011; PubMed: 21870810; DOI: 10.1021/bi2012355

実験手法

X-RAY DIFFRACTION (1.3 Å)