3PAC

Crystal structure of PduT a trimeric bacterial microcompartment protein with 4Fe-4S cluster binding site

3PAC の概要

• エントリーDOI: 10.2210/pdb3pac/pdb
• 分子名称: Shell protein (2 entities in total)
• 機能のキーワード: bmc domain, shell protein, electron transport
• 由来する生物種: Citrobacter freundii
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 21226.57

構造登録者

Pang, A.H.,Warren, M.J.,Pickersgill, R.W. (登録日: 2010-10-19, 公開日: 2010-12-01, 最終更新日: 2024-03-20)

主引用文献

Pang, A.,Warren, M.J.,Pickersgill, R.W.
Structure of PduT, a trimeric bacterial microcompartment protein with a 4Fe-4S cluster-binding site
Acta Crystallogr.,Sect.D, 67:91-96, 2011

PubMed Abstract: Propanediol metabolism in Citrobacter freundii occurs within a metabolosome, a subcellular proteinaceous bacterial microcompartment. The propanediol-utilization (Pdu) microcompartment shell is constructed from thousands of hexagonal-shaped protein complexes made from seven different types of protein subunit. Here, the structure of the bacterial microcompartment protein PduT, which has a tandem structural repeat within the subunit and forms trimers with pseudo-hexagonal symmetry, is reported. This trimeric assembly forms a flat approximately hexagonally shaped disc with a central pore that is suitable for a 4Fe-4S cluster. The essentially cubic shaped 4Fe-4S cluster conforms to the threefold symmetry of the trimer with one free iron, the role of which could be to supply electrons to an associated microcompartment enzyme, PduS.

PubMed: 21245529
DOI: 10.1107/S0907444910050201

実験手法

X-RAY DIFFRACTION (1.86 Å)