3PA9

Mechanism of inactivation of E. coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid (S-ADFA) pH 7.5

Summary for 3PA9

• Entry DOI: 10.2210/pdb3pa9/pdb
• Related: 3PAA
• Descriptor: Aspartate aminotransferase, 4-aminofuran-2-carboxylic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ... (6 entities in total)
• Functional Keywords: plp, pmp, sadfa, catalytic lysine, transferase
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 45391.77

Authors

Liu, D.,Pozharski, E.,Fu, M.,Silverman, R.B.,Ringe, D. (deposition date: 2010-10-19, release date: 2010-12-01, Last modification date: 2023-09-06)

• Primary citation: Liu, D.,Pozharski, E.,Fu, M.,Silverman, R.B.,Ringe, D.; Mechanism of inactivation of Escherichia coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid .; Biochemistry, 49:10507-10515, 2010; PubMed: 21033689; DOI: 10.1021/bi101325z

Experimental method

X-RAY DIFFRACTION (1.7 Å)