3P9W
Crystal structure of an engineered human autonomous VH Domain in complex with VEGF
Summary for 3P9W
Entry DOI | 10.2210/pdb3p9w/pdb |
Related | 3B9V |
Descriptor | Vascular endothelial growth factor A, human VEGF (3 entities in total) |
Functional Keywords | vh, cystine knot cytokine, vegf-r, signaling protein, signaling protein-immune system complex, signaling protein/immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P15692 |
Total number of polymer chains | 8 |
Total formula weight | 103516.51 |
Authors | Ma, X.,Wiesmann, C. (deposition date: 2010-10-18, release date: 2012-04-18, Last modification date: 2013-06-19) |
Primary citation | Ma, X.,Barthelemy, P.A.,Rouge, L.,Wiesmann, C.,Sidhu, S.S. Design of Synthetic Autonomous VH Domain Libraries and Structural Analysis of a VH Domain Bound to Vascular Endothelial Growth Factor. J.Mol.Biol., 425:2247-2259, 2013 Cited by PubMed: 23507309DOI: 10.1016/j.jmb.2013.03.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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