3P4T

Crystal structure of a putative acyl-CoA dehydrogenase from Mycobacterium smegmatis

Summary for 3P4T

• Entry DOI: 10.2210/pdb3p4t/pdb
• Related: 2oib
• Descriptor: Putative acyl-CoA dehydrogenase, 1,2-ETHANEDIOL, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(4aS,10aR)-7,8-dimethyl-2,4-dioxo-1,3,4,4a,5,10a-hexahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate, ... (4 entities in total)
• Functional Keywords: ssgcid, structural genomics, seattle structural genomics center for infectious disease, oxidoreductase, acyl-coa dehydrogenase, mycobacterium smegmatis, als collaborative crystallography
• Biological source: Mycobacterium smegmatis
• Total number of polymer chains: 2
• Total formula weight: 88062.46

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2010-10-07, release date: 2010-10-20, Last modification date: 2023-09-06)

• Primary citation: Baugh, L.,Phan, I.,Begley, D.W.,Clifton, M.C.,Armour, B.,Dranow, D.M.,Taylor, B.M.,Muruthi, M.M.,Abendroth, J.,Fairman, J.W.,Fox, D.,Dieterich, S.H.,Staker, B.L.,Gardberg, A.S.,Choi, R.,Hewitt, S.N.,Napuli, A.J.,Myers, J.,Barrett, L.K.,Zhang, Y.,Ferrell, M.,Mundt, E.,Thompkins, K.,Tran, N.,Lyons-Abbott, S.,Abramov, A.,Sekar, A.,Serbzhinskiy, D.,Lorimer, D.,Buchko, G.W.,Stacy, R.,Stewart, L.J.,Edwards, T.E.,Van Voorhis, W.C.,Myler, P.J.; Increasing the structural coverage of tuberculosis drug targets.; Tuberculosis (Edinb), 95:142-148, 2015; PubMed: 25613812; DOI: 10.1016/j.tube.2014.12.003

Experimental method

X-RAY DIFFRACTION (1.7 Å)