3OJF

Crystal Structure of the Bacillus cereus Enoyl-Acyl Carrier Protein Reductase with NADP+ and indole naphthyridinone (Complex form)

Summary for 3OJF

• Entry DOI: 10.2210/pdb3ojf/pdb
• Related: 3OJE
• Descriptor: Enoyl-[acyl-carrier-protein] reductase (FabL) (NADPH), (2E)-N-[(1,2-dimethyl-1H-indol-3-yl)methyl]-N-methyl-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)prop-2-enamide, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
• Functional Keywords: enoyl-acp reductase, tetramer, rossmann fold, nad(p) binding, oxidoreductase
• Biological source: Bacillus cereus
• Total number of polymer chains: 4
• Total formula weight: 116077.87

Authors

Kim, S.J.,Ha, B.H.,Kim, K.H.,Hong, S.K.,Suh, S.W.,Kim, E.E. (deposition date: 2010-08-22, release date: 2010-09-08, Last modification date: 2023-11-01)

• Primary citation: Kim, S.J.,Ha, B.H.,Kim, K.H.,Hong, S.K.,Shin, K.J.,Suh, S.W.,Kim, E.E.; Dimeric and tetrameric forms of enoyl-acyl carrier protein reductase from Bacillus cereus; Biochem.Biophys.Res.Commun., 400:517-522, 2010; PubMed: 20800575; DOI: 10.1016/j.bbrc.2010.08.083

Experimental method

X-RAY DIFFRACTION (2.2 Å)