3OEU
Structure of yeast 20S open-gate proteasome with Compound 24
3OEU の概要
エントリーDOI | 10.2210/pdb3oeu/pdb |
関連するBIRD辞書のPRD_ID | PRD_000944 |
分子名称 | Proteasome component Y7, Proteasome component C11, Proteasome component PRE2, ... (18 entities in total) |
機能のキーワード | 20s proteasome, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
由来する生物種 | Saccharomyces cerevisiae (Baker's yeast) 詳細 |
細胞内の位置 | Cytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451 |
タンパク質・核酸の鎖数 | 28 |
化学式量合計 | 707643.61 |
構造登録者 | |
主引用文献 | Blackburn, C.,Barrett, C.,Blank, J.L.,Bruzzese, F.J.,Bump, N.,Dick, L.R.,Fleming, P.,Garcia, K.,Hales, P.,Hu, Z.,Jones, M.,Liu, J.X.,Sappal, D.S.,Sintchak, M.D.,Tsu, C.,Gigstad, K.M. Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome. Bioorg.Med.Chem.Lett., 20:6581-6586, 2010 Cited by PubMed: 20875739DOI: 10.1016/j.bmcl.2010.09.032 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.6 Å) |
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