3OCN

Crystal structure of penicillin-binding protein 3 from Pseudomonas aeruginosa in complex with ceftazidime

3OCN の概要

• エントリーDOI: 10.2210/pdb3ocn/pdb
• 関連するPDBエントリー: 3OC2 3OCL
• 分子名称: penicillin-binding protein 3, 1-({(2R)-2-[(1R)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-oxoethyl]-4-carboxy-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyridinium (3 entities in total)
• 機能のキーワード: penicillin-binding proteins, pseudomonas aeruginosa, ceftazidime, structural genomics, oxford protein production facility, oppf, transpeptidase, cell wall biosynthesis, out periplasmic membrane, penicillin-binding protein-antibiotic complex, penicillin-binding protein/antibiotic
• 由来する生物種: Pseudomonas aeruginosa
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 61702.19

構造登録者

Sainsbury, S.,Bird, L.,Stuart, D.I.,Owens, R.J.,Ren, J.,Oxford Protein Production Facility (OPPF) (登録日: 2010-08-10, 公開日: 2010-11-10, 最終更新日: 2023-11-01)

• 主引用文献: Sainsbury, S.,Bird, L.,Rao, V.,Shepherd, S.M.,Stuart, D.I.,Hunter, W.N.,Owens, R.J.,Ren, J.; Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms; J.Mol.Biol., 405:173-184, 2011; PubMed: 20974151; DOI: 10.1016/j.jmb.2010.10.024

実験手法

X-RAY DIFFRACTION (2.61 Å)