3OCL

Crystal structure of penicillin-binding protein 3 from Pseudomonas aeruginosa in complex with carbenicillin

Summary for 3OCL

• Entry DOI: 10.2210/pdb3ocl/pdb
• Related: 3OC2 3OCN
• Descriptor: Penicillin-binding protein 3, CHLORIDE ION, (2R,4S)-2-[(1R)-1-{[(2S)-2-carboxy-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ... (5 entities in total)
• Functional Keywords: penicillin-binding proteins, pseudomonas aeruginosa, carbenicillin, structural genomics, oxford protein production facility, oppf, transpeptidase, cell wall biosynthesis, out periplasmic membrane, penicillin-binding protein-antibiotic complex, penicillin-binding protein/antibiotic
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 1
• Total formula weight: 61660.55

Authors

Sainsbury, S.,Bird, L.,Stuart, D.I.,Owens, R.J.,Ren, J.,Oxford Protein Production Facility (OPPF) (deposition date: 2010-08-10, release date: 2010-11-10, Last modification date: 2023-11-01)

• Primary citation: Sainsbury, S.,Bird, L.,Rao, V.,Shepherd, S.M.,Stuart, D.I.,Hunter, W.N.,Owens, R.J.,Ren, J.; Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms; J.Mol.Biol., 405:173-184, 2011; PubMed: 20974151; DOI: 10.1016/j.jmb.2010.10.024

Experimental method

X-RAY DIFFRACTION (2.3 Å)