3O9K

Influenza NA in complex with compound 6

Summary for 3O9K

DescriptorNeuraminidase, 5-(acetylamino)-2,6-anhydro-3,5-dideoxy-3-[(2E)-3-(4-methylphenyl)prop-2-en-1-yl]-D-glycero-D-galacto-non-2-enonic acid (2 entities in total)
Functional Keywordsglycosidase, hydrolase
Biological sourceInfluenza A virus (A/duck/Ukraine/1/1963(H3N8))
Cellular locationVirion membrane (By similarity) Q07599
Total number of polymer chains1
Total molecular weight43260.55
Authors
Russell, R.J.,Kerry, P.S. (deposition date: 2010-08-04, release date: 2010-12-15, Last modification date: 2011-07-13)
Primary citation
Rudrawar, S.,Dyason, J.C.,Rameix-Welti, M.A.,Rose, F.J.,Kerry, P.S.,Russell, R.J.,van der Werf, S.,Thomson, R.J.,Naffakh, N.,von Itzstein, M.
Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase.
Nat Commun, 1:113-113, 2010
PubMed: 21081911 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms1114
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4945 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.301222.3%10.0%3.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution