Influenza NA in complex with compound 5

Summary for 3O9J

DescriptorNeuraminidase, 5-(acetylamino)-2,6-anhydro-3,5-dideoxy-3-prop-2-en-1-yl-D-glycero-D-galacto-non-2-enonic acid, CALCIUM ION, ... (5 entities in total)
Functional Keywordsneuraminidase, hydrolase
Biological sourceInfluenza A virus (A/duck/Ukraine/1/1963(H3N8))
Cellular locationVirion membrane (By similarity) Q07599
Total number of polymer chains1
Total molecular weight43431.71
Russell, R.J.,Kerry, P.S. (deposition date: 2010-08-04, release date: 2010-12-15, Last modification date: 2011-07-13)
Primary citation
Rudrawar, S.,Dyason, J.C.,Rameix-Welti, M.A.,Rose, F.J.,Kerry, P.S.,Russell, R.J.,van der Werf, S.,Thomson, R.J.,Naffakh, N.,von Itzstein, M.
Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase.
Nat Commun, 1:113-113, 2010
PubMed: 21081911 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms1114
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.282261.3%7.0%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution