3O4K

Crystal structure of the complex of peptidoglycan recognition protein (PGRP-S) and lipoteichoic acid at 2.1 A resolution

Summary for 3O4K

Entry DOI	10.2210/pdb3o4k/pdb
Descriptor	Peptidoglycan recognition protein 1, (2S)-1-({3-O-[2-(acetylamino)-4-amino-2,4,6-trideoxy-beta-D-galactopyranosyl]-alpha-D-glucopyranosyl}oxy)-3-(heptanoyloxy)propan-2-yl (7Z)-pentadec-7-enoate, GLYCEROL, ... (5 entities in total)
Functional Keywords	immune response, secreted, antimicrobial, pgrp, antibiotic, peptidoglycan binding, immune system
Biological source	Camelus dromedarius (dromedary)
Cellular location	Secreted (By similarity): Q9GK12
Total number of polymer chains	4
Total formula weight	77063.00
Authors	Sharma, P.,Dube, D.,Sinha, M.,Kaur, P.,Sharma, S.,Singh, T.P. (deposition date: 2010-07-27, release date: 2010-08-25, Last modification date: 2023-11-01)
Primary citation	Sharma, P.,Dube, D.,Singh, A.,Mishra, B.,Singh, N.,Sinha, M.,Dey, S.,Kaur, P.,Mitra, D.K.,Sharma, S.,Singh, T.P. Structural basis of recognition of pathogen-associated molecular patterns and inhibition of proinflammatory cytokines by camel peptidoglycan recognition protein J.Biol.Chem., 286:16208-16217, 2011 Cited by PubMed: 21454594 DOI: 10.1074/jbc.M111.228163 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.11 Å)

Structure validation