3O0T

Crystal structure of human phosphoglycerate mutase family member 5 (PGAM5) in complex with phosphate

Summary for 3O0T

• Entry DOI: 10.2210/pdb3o0t/pdb
• Related: 3MXO
• Descriptor: Serine/threonine-protein phosphatase PGAM5, mitochondrial, PHOSPHATE ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, phosphoglycerate mutase family member 5, pgam5, bxlbv68, mgc5352 protein, serine/threonine phosphatase, mitochondrial protein, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion outer membrane ; Single-pass membrane protein : Q96HS1
• Total number of polymer chains: 2
• Total formula weight: 47069.19

Authors

Chaikuad, A.,Alfano, I.,Picaud, S.,Filippakopoulos, P.,Barr, A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Takeda, K.,Ichijo, H.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2010-07-20, release date: 2010-10-06, Last modification date: 2023-07-26)

• Primary citation: Chaikuad, A.,Filippakopoulos, P.,Marcsisin, S.R.,Picaud, S.,Schroder, M.,Sekine, S.,Ichijo, H.,Engen, J.R.,Takeda, K.,Knapp, S.; Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly.; Structure, 25:1089-1099.e3, 2017; PubMed: 28648608; DOI: 10.1016/j.str.2017.05.020

Experimental method

X-RAY DIFFRACTION (1.9 Å)