3NYV

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with non-specific inhibitor WHI-P180

3NYV の概要

• エントリーDOI: 10.2210/pdb3nyv/pdb
• 関連するPDBエントリー: 3i79 3i7b 3i7c 3mwu 3n51 3ncg
• 分子名称: Calmodulin-domain protein kinase 1, 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE (3 entities in total)
• 機能のキーワード: serine/threonine protein kinase, transferase, calcium-binding, atp-binding, calmodulin, ef hand, bumped kinase inhibitor, structural genomics, medical structural genomics of pathogenic protozoa, msgpp, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Toxoplasma gondii
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 56274.54

構造登録者

Larson, E.T.,Merritt, E.A.,Medical Structural Genomics of Pathogenic Protozoa (MSGPP) (登録日: 2010-07-15, 公開日: 2010-07-28, 最終更新日: 2023-11-22)

• 主引用文献: Larson, E.T.,Ojo, K.K.,Kim, J.E.,Verlinde, C.L.M.J.,Buckner, F.S.,Hol, W.G.J.,Merritt, E.A.,Van Voorhis, W.C.; Binding modes of non-specific inhibitors of Calcium-Dependent Protein Kinase 1 (CDPK1) from T. gondii and C. parvum; To be Published,

実験手法

X-RAY DIFFRACTION (1.88 Å)