3NWA

Glycoprotein B from Herpes simplex virus type 1, W174R mutant, low-pH

Summary for 3NWA

• Entry DOI: 10.2210/pdb3nwa/pdb
• Related: 2GUM 3NW8 3NWD 3NWF
• Descriptor: Envelope glycoprotein B, 2-acetamido-2-deoxy-beta-D-glucopyranose, MESO-ERYTHRITOL, ... (4 entities in total)
• Functional Keywords: coiled-coil, envelope glycoprotein, membrane fusion, viral protein, glycoprotein b, herpesvirus 1, hsv-1, membrane
• Biological source: Human herpesvirus 1 (HHV-1)
• Cellular location: Virion membrane; Single-pass type I membrane protein (By similarity): P06437
• Total number of polymer chains: 4
• Total formula weight: 316872.56

Authors

Stampfer, S.D.,Lou, H.,Cohen, G.H.,Eisenberg, R.J.,Heldwein, E.E. (deposition date: 2010-07-09, release date: 2010-12-01, Last modification date: 2023-09-06)

• Primary citation: Stampfer, S.D.,Lou, H.,Cohen, G.H.,Eisenberg, R.J.,Heldwein, E.E.; Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1.; J.Virol., 84:12924-12933, 2010; PubMed: 20943984; DOI: 10.1128/JVI.01750-10

Experimental method

X-RAY DIFFRACTION (2.2629 Å)