3NWA

Glycoprotein B from Herpes simplex virus type 1, W174R mutant, low-pH

3NWA の概要

• エントリーDOI: 10.2210/pdb3nwa/pdb
• 関連するPDBエントリー: 2GUM 3NW8 3NWD 3NWF
• 分子名称: Envelope glycoprotein B, 2-acetamido-2-deoxy-beta-D-glucopyranose, MESO-ERYTHRITOL, ... (4 entities in total)
• 機能のキーワード: coiled-coil, envelope glycoprotein, membrane fusion, viral protein, glycoprotein b, herpesvirus 1, hsv-1, membrane
• 由来する生物種: Human herpesvirus 1 (HHV-1)
• 細胞内の位置: Virion membrane; Single-pass type I membrane protein (By similarity): P06437
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 316872.56

構造登録者

Stampfer, S.D.,Lou, H.,Cohen, G.H.,Eisenberg, R.J.,Heldwein, E.E. (登録日: 2010-07-09, 公開日: 2010-12-01, 最終更新日: 2023-09-06)

• 主引用文献: Stampfer, S.D.,Lou, H.,Cohen, G.H.,Eisenberg, R.J.,Heldwein, E.E.; Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1.; J.Virol., 84:12924-12933, 2010; PubMed: 20943984; DOI: 10.1128/JVI.01750-10

実験手法

X-RAY DIFFRACTION (2.2629 Å)