3NUL

Profilin I from Arabidopsis thaliana

3NUL の概要

• エントリーDOI: 10.2210/pdb3nul/pdb
• 分子名称: PROFILIN I, SULFATE ION, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: profilin, cytoskeleton, actin binding protein
• 由来する生物種: Arabidopsis thaliana (MOUSE EAR CRESS)
• 細胞内の位置: Cytoplasm, cytoskeleton (By similarity): Q42449
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14568.92

構造登録者

Thorn, K.,Christensen, H.E.M.,Shigeta, R.,Huddler, D.,Chua, N.-H.,Shalaby, L.,Lindberg, U.,Schutt, C.E. (登録日: 1996-11-27, 公開日: 1997-12-03, 最終更新日: 2024-06-05)

主引用文献

Thorn, K.S.,Christensen, H.E.,Shigeta, R.,Huddler, D.,Shalaby, L.,Lindberg, U.,Chua, N.H.,Schutt, C.E.
The crystal structure of a major allergen from plants.
Structure, 5:19-32, 1997

PubMed Abstract: Profilins are small eukaryotic proteins involved in modulating the assembly of actin microfilaments in the cytoplasm. They are able to bind both phosphatidylinositol-4,5-bisphosphate and poly-L-proline (PLP) and thus play a critical role in signaling pathways. Plant profilins are of interest because immunological cross-reactivity between pollen and human profilin may be the cause of hay fever and broad allergies to pollens.

PubMed: 9016723
DOI: 10.1016/S0969-2126(97)00163-9

実験手法

X-RAY DIFFRACTION (1.6 Å)